국립부경대학교 | 생물공학과
홈
교수소개
교수소개

교수소개

교수소개

교수사진

박남규교수(학과장)

  • 주소 : (48513) 부산광역시 남구 용소로 45 부경대학교 수산과학대학 생물공학과
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1981 - 1985 부산대학교 화학과 이학사

1986 - 1988 일본 九州大學 생화학 이학석사

1988 - 1991 일본 九州大學 생화학 이학박사

1991 - 1992 일본 三菱(Mitsubishi)化成 生命科學硏究所 특별연구원

1992 - 1994 부산수산대학교 전임강사

1994 - 1996 부산수산대학교 조교수

1996 - 2003 부경대학교 부교수

2001 - 2003 North Carolina State University 방문교수

2003 - 현재 부경대학교 교수

해양생물로부터 생리활성물질 정제
정제된 물질의 구조-활성 연구

유기화학, 생체분자구조분석, 생리활성물질

  • N. G. Park, Y. Yamato, S. Lee and G. Sugihara (1995) Interaction of mastoparan-B from of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity. Biopolymers, 36, 793-801.
  • N. G. Park, K-H. Kim, S-W. Kang, S. Lee, H. Aoyagi and G. Sugihara (1995) Morphological changes of bacteria membranes induced by amphipathic antimicrobial peptides. Japan Peptide Chemistry, 373-376.？
  • Y. Yamato, N. G. Park, S. Lee and G. Sugihara (1995) Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity. Japan Peptide Chemistry, 317-320.？
  • N. G. Park, K-H. Kim, J-S. Park, S-W. Kang, T. Kiyota, S. Lee and G. Sugihara (1996) Intraction of mastoparan B and its Ala-substituted analogs with phospholipid bilayers. Japan Peptide Chemistry, 793-801.？
  • N. G. Park, Y. Yamato, S. Lee, G. Sugihara, J-S. Park and S-W. Kang (1996) Interaction of mastoparan B from venom of a hornet Vespa Basalis with phospholipid matrices, Bull. Korean Chem. Soc., 17, 239-244.？
  • Lee, H-H., Park, J-S., Park, N. G. (1996) Studies on the structure-activity of antimicrobial peptide isolated from horseshoe crab. J. Fish Pathol, 9, 65-77.
  • M-D. Huh, N. G. Park, H-H. Lee, J-S. Park, S-W. Kang, T. Kunitake, S. Lee and G. Sugihara (1996) Structure-Activity Relationship of Tachykinin Peptides from Fish. Japan Peptide Chemistry, 185-188.？
  • N. G. Park, K. H. Kim, J-S. Park, S-W. Kang, T. Kiyota, S. Lee, and G. Sugihara. (1996) Interaction of mastoparan B and its Ala-substituted analogs with phospholipid bilayers. Japan Peptide Chemistry, 213-216.
  • N. G. Park, J-K. Seo, H-J. Ku, S. Lee, G. Sugihara, K-H. Kim, J-S. Park and S-W. Kang (1997) Conformation and Biological activity of Mastoparan B and its analogs Ⅰ. Bull. Korean Chem. Soc., 18, 10-14.？
  • J-S. Park, K. O. Jung, J. C. Kim, K. H. Kim, N. G. Park, H. S. Suh, and S-W. Kang. (1997) Interactions of mastoparan B with phospholipid vesicles: Relationships with fusion and leakage actions (I). Bull. Korean Chem. Soc., 18, 258-261.？
  • Park, N. G., Seo, J-K., Ku, H-J., Kim, S-H., Lee, S., Sugihara, G., Kim, K-H., Park, J-S., and Kang S-W. (1997) Interaction of mastoparan B and its Ala-substituted analogs with phospholipid bilayers, Bull. Korean Chem. Soc., 18, 933-938.？
  • Ku, H-J., Seo, J-K., Kim, E-H., Huh, M-D., Chun, J-K., Park, J-S., Kang, S-W., and Park, N. G. (1997) Conformation and Biological Activity of the Neuropeptide γ, J. Korean Fish. Soc. 30, 18-22.
  • N. G. Park, C-H. Kim, J-K. Chung, M-D. Huh, J-S. Park and S-W. Kang (1998) Morphological changes of biomembranes by amphiphilic basic peptides Mastoparan B and 43. J. Microbiol., 36, 179-183.？
  • S. Y. Lee, N. G. Park and M-U. Choi (1998) Effect of mastoparan B and its analogs on the phospholipase D activity in L1210 cells. FEBS Letters, 432, 50-54.？
  • J-S. Park, I-C. Jeong, A. Kim, and N. G. Park, D-K. Kim, H. Suh, and S-W. Kang (1999) 1H-NMR studies of the interaction between cytochrome C3 and Ferredoxin I from D. Vulgaris Miyazkki F, Bull. Korean Chem. Soc., 20(5), 543-546？
  • K. Yu, S. Kang, N. Park, J. Shin, and Y. Kim (2000) Relationship between the tertiary structures of mastoparan B and its analogs and their lytic activities studied by NMR spectroscopy, J. Peptide Res., 54, 51-62？
  • J-K. Seo, C-H. Kim, G. T. Kim, H-J. Go, M. J. Shin, E. J. Kim, S. Lee, G. Sugihara, and N. G. Park (2000) Purification and characterization of a novel antimicrobial peptide from the skin of hagfish, Eptatretus burgeri, Japan Pep. Chem. 179-182？
  • E. J. Kim, J-K. Seo, C-H. Kim, H. T. Kim, Y. Takano, H-O. Kamiya, S. Lee, G. Sugihara, and N. G. Park (2000) Structure and biological activity of the neuropeptide γ, Japan Pep. Chem. 467-470？
  • C-H. Kim, E. J. Kim, J-K. Seo, H. T. Kim, Y. Muneoka, and N. G. Park (2000) Purification and characterization of SP-related peptide from the African lungfish, Protopterus dolloi, Japan, Pep. Chem. 183-186？
  • C-H. Kim, S. J. Seo, E-Y Hwang, E. J. Kim , H-J GO, and N. G. Park (2001) Purification of myomodulin A and myomodulin E from the central nervous system of the sea hare, Aplisia kurodai, J. Korean Fish. Soc. 279-284？
  • Eun Jung Kim,, Chan-Hee Kim, Jung-Kil Seo, Hye-Jin Go, S. Lee, Y. Takano, Joon Ki Chung, Yong-Ki Hong, Nam Gyu Park (2005). Structure-activity relationship of neuropeptide γ derived from mammalian and fish. J. Peptide Res. 66(6):395-403？
  • Sang Uk Lim, Jung Soo Seo, Moo Sang Kim, Sang Jung Ahn, Hyun Do Jeong, Ki Hong Kim, Nam Gyu Park, Joong Kyun Kim, Joon Ki Chung, Hyung Ho Lee (2005). Molecular cloning and characterization of Cathepsin B from a scuticociliate, Uronema marinum. Comparative Biochemistry And Physiology Part B, 142(3):283-92？
  • Ji-Young Cho, Jae-Suk Choi, Nam Gyu Park, Hyun-Woung Shin, Yong-Ki Hong (2006). Antifouling properties of plasticizers BPBG and DNOP against algal spore and mussel attachment. Botanica Marina (Bot. Mar.) 49, 263 ？ 265.？
  • Chan-Hee Kim, Eun Jung Kim, Hye-Jin Go, Hyung Ho Lee, Yong-Ki Hong, Hyung-Rak Kim, Joon Ki Chung, Jang-Su Park, Yojiro Muneoka and Nam Gyu Park (2006). Purification and Characterization of Substance P-related Peptide from the Body of the African Lungfish, Protopterus dolloi. Bull. Korean Chem. Soc. 27(7), 1015-1019.？
  • Chan-Hee Kim, Eun Jung Kim, Hye-Jin Go, Hyung Ho Lee, Yong-Ki Hong, Hyung-Rak. Kim, Joon Ki Chung, Jang-Su Park, Yojiro Muneoka,and Nam Gyu Park (2006). Purification and Characterization of [Ala2]-Neuromedin N from the Visceral Tissue of the African Lungfish, Protopterus dolloi. Bull. Korean Chem. Soc. 27(11), 1733-1736.？
  • Mohammed Nurul Absar Khan, Ji-Young Cho,Min-Chul Lee, Ji-Young Kang, Nam Gyu Park, Hitoshi Fujii, and Yong-Ki Hong (2007). Isolation of Two Anti-inflammatory and One Pro-inflammatory Polyunsaturated Fatty Acids from the Brown Seaweed Undaria pinnatifida. Journal Of Agricultural And Food Chemistry, 55, 6984-6988？
  • Hai Quoc Luyen Ji-Young Cho, Hyun-Woung Shin, Nam Gyu Park, Yong-Ki Hong (2007). Microalgal growth enhancement by levoglucosan isolated from the green seaweed Monostroma nitidum. Journal Of Applied Phycology 19(2), 175-180.？
  • Hyun-Ji Cho, Jeong Han Kang, Jong-Young Kwak,Tae-Sung Lee, In-Seon Lee, Nam Gyu Park, Hiroo Nakajima, Junji Magae and Young-Chae Chang (2007). Ascfuranone suppresses PMA-mediated matrix metalloproteinase 9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. Carcinogenesis 28(5).1104-110.？
  • Andre Kim, Chun-Ri Li, Chun-Feng Jin, Keun Woo Lee, Sang-Hoon Lee, Kwang-Jae Shon, Nam Gyu Park, Dong-Kyoo Kim, Shin-Won Kang, Yoon-Bo Shim, Jang-Su Park (2007). A sensitive and reliable quantification method for Bisphenol A based on modified competitive ELISA method. Chemosphere 68(7), 1204-1209.？
  • Mohammed Nurul Absar Khan, Min-Chul Lee, Ji-Young Kang, Nam Gyu Park, Hitoshi Fujii, Yong-Ki Hong (2008). Effects of the Brown Seaweed Undaria pinnatifida on Erythematous Inflammation Assessed Using Digital Photo Analysis. Phytotherapy Research 22(5),634-639.？
  • Joon Bum Jeong, Ho Yeoul Kim, Lyu Jin Jun, Ji Hyo Lyu, Nam Gyu Park, Joong Kyun Kim, Hyun Do Jeong (2008). Outbreaks and risks of infectious spleen and kidney mecrosis virus disease in freshwater or normental fishes. Diseases aquatic organism 78,209-215？
  • Quoc-Hai Luyen, Ji-Young Cho, Jae-Suk Choi, Ji-Young Kang, Nam Gyu Park and Yong-Ki Hong (2009). Isolation of algal sporelytic C17 fatty acid from the crustose coralline seaweed Lithophyllum yessoense. Journal of applied phycology 21, 423-427.
  • A-Reum Kim, Tai-Sun Shin, Min-Sup Lee, Ji-Young Park, Kyoung-Eun Park, Na-Young Yoon, Jong-Soon Kim, Jae-Sue Choi, Byeong-Churl Jang, Dae-Seok Byun, Nam Gyu Park and Hyeung-Rak Kim (2009). Isolation and Identification of Phlorotannin from Ecknolia stolonifera with Antioxidant and Anti-inflammatory Properties. Journal of Agricultural And Food Chemistry 57(9), 3483-3489.？
  • Ju Eun Jea, Sang Jung Ahn, Na Young Kim, Jung Soo Seo, Moo-Sang Kim, Nam Gyu Park, Joong Kyun Kim, Joon Ki Chung, Hyung Ho Lee (2009). Molecular cloning, expression analysis and enzymatic characterization of cathepsin K from olive flounder (Paralichthys olivaceus). Comparative Biochemistry And Physiology Part A 154(4),474-485.？
  • Edward J. Noga, Uma Silphaduang, Nam Gyu Park, Jung Kil Seo, Jeana Stephenson, Shannon Kozlowicz (2009). Piscidin 4, a Novel Member of the Piscidin Family of Antimicrobial Peptides. Comparative Biochemistry and Physiology, Part B 152, 299-305.？
  • Hye-Jin Go, Eun Hee Jo, Jung-Kil Seo, Yong-Ki Hong, Hyung Ho Lee, Gun Do Kim, Tae Wook Park, Edward J. Noga, Nam Gyu Park (2011). Isolation and characterization of a novel myoactive tetradecapeptide-related peptide isolated from the brain of the squid, Todarodes pacificus. Peptides,32, 447-453.？
  • N.G. Park, U. Silphaduang, H.S. Moon, J.-K. Seo, J. Corrales, and E.J. Noga (2011). Structure-activity relationships of piscidin 4, a piscine antimicrobial peptide. Biochemistry 50, 3288-3299.？
  • Jung-Kil Seo, Hye-Jin Go, Ho Sung Moon, Min Jeong Lee, Yong-Ki Hong, Hyun Do Jeong, Bo-Hye Nam, Tae Hyun Park, and Nam Gyu Park (2012). Interaction of Apidaecin Ib with Phospholipid Bilayers and its Edwardsiella Species-specific Antimicrobial Activity. Bull. Korean Chem. Soc., 33(1), 115-122.？
  • Bo-Hye Nam, Jung-Kil Seo, Hye-Jin Go, Min Jeong Lee, Young-Ok Kim, Dong-Gyun Kim, Sang-Jun Lee and Nam Gyu Park (2012). Purification and characterization of an antimicrobial histone H1-like protein and its gene from the testes of olive flounder, Paralichthys olivaceus. Fish & shellfish immunology 33, 92~98.？
  • Jung-Kil Seo, Min Jeong Lee, Hye-Jin Go, Tae Hyun Park, and Nam Gyu Park (2012). Purification and characterization of YFGAP, a GAPDH-derived novel antimicrobial peptide, from the skin of yellowfin tuna, Thunnus albacares. Fish & shellfish immunolgy(In press).？
  • Jung-Kil Seo, Min Jeong Lee, Hye-Jin Go, Gun Do Kim, Hyun Do Jeong, Bo-Hye Nam, and Nam Gyu Park (2013). Purification and Antimicrobial Function of Ubiquitin Isolated from the Gill of Pacific Oyster, Crassostrea gigias. Molecular Immunology.
  • Jung-Kil Se, Min Jeong Lee, Bo-Hye Nam, Nam Gyu Park (2013). cgMolluscidin, a novel dibasic residue repeat rich antimicrobial peptide, purified from the gill of the Pacific oyster, Crassostrea gigas. Fish & Shellfish Immunology 35, 480-488.？
  • Hye Jin Bak, Moo-Sang Kim, Na Young Kim, Hye-Jin Go, Jin Woo Han, Hyae In Jo, Sang Jung Ahn, Nam Gyu Park, Joon Ki Chung, Hyung Ho Lee (2013). Molecular Cloning, Expression, and Enzymatic Analysis of Cathepsin X from Starfish (Asterina pectinifera). Appl Biochem Biotechnol 169:847？861？
  • Jung-Kil Seo, Min Jeong Lee, Hyun-Gyo Jung, Hye-Jin Go, Young Ja Kim,？
  • Nam Gyu Park (2014) Antimicrobial function of SHbAP, a novel hemoglobin b chain-related antimicrobial peptide, isolated from the liver of skipjack tuna, Katsuwonus pelamis Fish & Shellfish Immunology 37 173-183？
  • Jung-Kil Seo a, Min Jeong Lee b, Hye-Jin Go b, Yeon Jun Kim c, Nam Gyu Park (2014). Antimicrobial function of the GAPDH-related antimicrobial peptide in the skin of skipjack tuna, Katsuwonus pelamis Fish & Shellfish Immunology 36 571e581？
  • Bo-Hye Nam, Ji-Young Moon, Eun-Hee Park, Young-Ok Kim, Dong-Gyun Kim, Hee Jeong Kong, Woo-Jin Kim, Young Ju Jee, Cheul Min An, Nam Gyu Park and Jung-Kil Seo (2014). Antimicrobial Activity of Peptides Derived from Olive Flounder Lipopolysaccharide Binding Protein/Bactericidal Permeability-Increasing Protein (LBP/BPI) Mar. Drugs 12, 5240-5257;
  • Chan-Hee Kim, Hye-jin Go and Nam Gyu Park (2015). Two myomodulin isolatied from central nervous system of northwest pacific sea hare, Aplysia kurodai, and Their activities on other mollusks Protein & Peptide Letters 22, 341-347？
  • Bo-Hye Nam, Jung-Kil Seo, Min Jeong Lee, Young-Ok Kim, Dong-Gyun Kim ,Cheul Min An, Nam Gyu Park (2015). Functional analysis of Pacific oyster (Crassostrea gigas) b-thymosin: Focus on antimicrobial activity. Fish & Shellfish Immunology 45 167-174？
  • Chan-Hee Kim, Eun Jung Kim, Hye-Jin Go, Hye Young Oh, Ming Lin, Maurice R. Elphick, and Nam Gyu Park (2016). Identification of a novel starfish neuropeptide that acts as a muscle relaxant J Neurochem. 2016 Jan 23. doi: 10.1111

바이오메디컬사이언스 실험실 (Biomedical Sciences Laboratory)